Burton Albion moved to the top of Sky Bet League 2 table after cruising to a 3-1 win at Dagenham & Redbridge.Manager Jimmy Floyd Hasselbaink's substitution played a crucial role as Abdenasser El Khayati put them ahead before teeing up Damian McCrory late on.
Dagenham, without ill boss Wayne Burnett, had threatened to cause an upset when Alex Jakubiak opened the scoring, only for Adam McGurk to smash home the leveller four minutes later.
Previous leaders Shrewsbury Town slipped to second as they lost 2-1 at Tranmere Rovers after first-half goals from Rory Donnelly and Danny Holmes.
Third-placed Wycombe Wanderers kept up the pressure at the top as goals from Aaron Pierre, Matthew McClure and Fred Onyedinma earned them a 3-2 win at Carlisle United.
Reuben Reid was Plymouth Argyle's Devon derby hero with a hat-trick against Exeter City in a comfortable 3-1 win at St James' Park in the day's early kick-off.
Argyle's top scorer saw his opener cancelled out by Arron Davies but he kept his cool to convert a penalty. Team-mate Olly Lee picked up a straight red but Argyle were not to be denied with Reid bundling home a third to claim the match ball.
There was also a treble for Matt Tubbs as Portsmouth won away in League 2 for just the second time this season as they put Cambridge to the sword in an emphatic 6-2 win.
Andrew Tutte's goal saw Bury climb back into the Play-Off places as they saw off Hartlepool United 1-0 while in stark contrast Newport County's own promotion dream took a hit after Morecambe held out for a 1-0 victory after Jack Redshaw's strike.
A last-minute winner from substitute David Connolly helped AFC Wimbledon see off Luton Town 3-2. The Hatters had battled back from 2-0 down, only for veteran forward Connolly to steal victory.
Alex MacDonald struck twice as Oxford crushed Mansfield Town 3-0 to ease their relegation fears while substitute Ben Kennedy inspired Stevenage to a dramatic 4-2 win over Southend United.
Elsewhere, Northampton Town comfortably saw off York City 3-0 to record their sixth win in eight games.