There are five fixtures in Sky Bet League 2 taking place this weekend where one of the sides has failed to overcome the opposition in all previous meetings.Some sides have been waiting longer than others, but we're taking a look at each game as the clubs seek their first wins against certain opposition.
Luton Town v Burton Albion
One of the biggest matches of the weekend sees Luton and Burton face off at Kenilworth Road.
The two sides have only met once in their history, back in November's reverse fixture, with Jimmy Floyd Hasselbaink's men winning 1-0 that day.
If the Hatters can square the scores on Saturday then their Play-Off push will be firmly back on track after they ended a seven-match losing streak last weekend, but they will be up against it with the Brewers looking to cement their lead at the top of the division.
Newport County v Bury
Another side looking for a first win is Bury, who have gone three games without finding a way to beat Newport.
The pair's first two encounters came during the last campaign, with both games finishing goalless. However, the Exiles didn't mess around earlier this term when Aaron O'Connor found the net after just three minutes.
O'Connor went on to score a hat-trick in a 3-1 victory, and now the Shakers make the journey to Rodney Parade looking to even things up in their quest for automatic promotion.
Morecambe v Portsmouth
A mid-table battle takes place at the Globe Arena where 12th-placed Morecambe host Portsmouth, who sit two places below in 14th.
The Shrimps have gone three games without success against Pompey, but they will be pleased to be on home soil this weekend.
Their two visits to Fratton Park have seen them succumb to successive 3-0 defeats, but hey did take a point at home to Portsmouth in January last season. If they can go one better this time around, then they will open up a four-point cushion over Andy Awford's side with four games remaining.
Stevenage v Northampton Town
Stevenage play host to Northampton on the back of a five-game winless streak against their weekend opponents, stretching back 10 years.
That encounter came in the FA Cup, when the then-Conference outfit held the Cobblers to a 2-2 draw. But that is as good as it gets for Boro, who have failed to score in the four defeats since that day, including the cup replay which finished 2-0 to Northampton.
The first league meetings were in 2010/11, when the Cobblers won 1-0 and 2-0, and they secured a 1-0 success over Graham Westley's side back in November thanks to a Marc Richards goal.
If Stevenage can open their account this weekend then it will be a massive boost to their Play-Off ambitions, while all but ending Northampton's top-seven hopes in the process.
AFC Wimbledon v Oxford United
The above fixtures pale in comparison to Wimbledon's record against Oxford, with the Dons drawing one and losing eight of the previous nine clashes.
Wimbledon had lost the first eight meetings, including four non-league encounters in which they failed to find the net.
In fact, the Dons haven't scored in seven of the fixtures. But one of those did result in their only point, and that came earlier this term at the Kassam Stadium where AFC finally brought their losing run agains the U's to an end.
You can see follow the action from all these games with our live Twitter feed - @SkyBetLeague2