Tuesday 8th October
Holders Crewe Alexandra were dumped out of the Johnstone's Paint Trophy after losing 4-0 to League 2 Fleetwood Town.
First-half goals from David Ball and Jon Parkin gave the hosts the advantage at the break before Nathan Pond and Matty Blair finished the job in the second half.
Chesterfield, the 2012 winners, reached the Northern Section quarter-finals following a 1-0 win over rivals Mansfield Town.
Gary McSheffrey scored the only goal as the Spireites gained a measure of revenge for the 1-0 home defeat in League 2 against the same opponents 10 days earlier.
Sheffield United's miserable run of form continued as James Poole's strike gave Hartlepool United a 1-0 win at Bramall Lane.
Notts County knocked out Wolverhampton Wanderers 3-1 on penalties following a goalless draw at Molineux, with Bjorn Sigurdarson, Kevin Foley and James Henry all missing their spot-kicks for the hosts.
Rotherham United progressed following a convincing 3-0 win at York City.
Chris Smith's own-goal gave the visitors the lead before second-half goals from Kieran Agard and Alex Revell secured a comfortable victory.
Danny Philliskirk and James Wesolowski scored in the opening 10 minutes as Oldham Athletic recorded a 2-0 win at Preston North End, while Joe Rafferty's goal helped Rochdale to a 1-0 victory at Port Vale.
Ryan Williams and Andrew Fleming missed penalties as 2011 winners Carlisle United beat Morecambe 4-3 on penalties following a goalless draw at the Globe Arena.
Dagenham and Redbridge scored four goals in an incredible eight-minute spell to dump last season's beaten finalists Southend United out of the Johnstone's Paint Trophy with a 5-2 win.
Southend substitute Cauley Woodrow netted twice early in the second half to cancel out Zavon Hines' first-half opener before the Daggers ran riot.
Brian Saah, Hines, Chris Dickson and Afolabi Obafemi all scored as the visitors booked their place in the next round in emphatic fashion.
Newport County came from two goals down to beat 10-man Crawley Town.
Emile Sinclair and Michael Jones put the League 1 side in control, with Chris Zebroski responding for Newport with half-time approaching. Adam Chapman levelled from the spot after James Hurst saw red and Connor Essam put through his own goal as Newport progressed.
Francois Zoko scored on his debut as Stevenage produced a comeback of their own to dump out Milton Keynes Dons 2-1.
Shaun Williams gave the Dons the lead from the penalty spot but goals from Zoko and a Filipe Morais spot-kick edged it for Boro.
League 1 leaders Leyton Orient continued their excellent start to the season by knocking Coventry City out on penalties. The game ended in a goalless draw before the Sky Blues missed twice in the shoot-out.
Bristol City's campaign went from bad to worse with a 2-1 defeat at Wycombe Wanderers.
Billy Knott and Matt Bloomfield gave the League 2 side a two-goal cushion. Brendan Moloney got one back for the Robins but it was nothing more than a consolation.
Portsmouth went through with victory by the same scoreline against Oxford United.
Patrick Agyemang and Yassin Moutaouakil scored for Pompey before James Constable gave the home fans something to shout about in defeat.
A Martin Taylor own goal and a Grant McCann penalty gave Peterborough United a 2-1 victory over Brentford, who got on the scoresheet through Ben Nugent.
Swindon Town fought back from a goal down to beat League 2 Plymouth Argyle 2-1.
Andre Blackman put the Pilgrims in front but goals from Jack Barthram and Nick Ajose sent the hosts through.