Barnsley v Reading
Barnsley, who have slumped to the foot of the Sky Bet Championship table, host Reading on Tuesday night.
The Tykes have succumbed to four successive defeats, and have conceded 24 goals in their nine games to date - by far the worst defensive record in the division.
Nigel Adkins' Reading are up to sixth following three victories on the bounce, against Leeds United, Derby County and, most recently, Birmingham City.
Birmingham City v Millwall
Birmingham's next assignment is against a resurgent Millwall.
The Blues' loss to Reading was their third in four matches, while Millwall have chalked up three successive victories after going without a win in their first six matches.
The Lions haven't got the better of Birmingham since 1996 but the last two meetings between the two clubs have ended level.
Blackburn Rovers v Watford
Watford have recorded three consecutive wins and travel to Blackburn Rovers.
The Hornets have overcome Doncaster, Barnsley and Wigan Athletic over recent weeks, following a four-game winless run, and they sit fourth.
Blackburn have also improved after a slow start - the Ewood Park outfit have lost once in six and beat Bournemouth on Saturday.
Jordan Rhodes nets Blackburn's second goal in their 3-1 victory at Bournemouth last time out
Blackpool v Bolton Wanderers
Bolton Wanderers' search for a first victory continues on Tuesday when they visit Blackpool.
Dougie Freedman's team needed a last-gasp Alex Baptiste equaliser to rescue a point at home to Yeovil Town on Saturday, leaving them with four points from nine games - all draws. You have to go back to 1902 for the last time when the club failed to win any of their first nine.
The Seasiders' blistering start has come to an end and they are without a victory in three, drawing their last two, against Leicester and Huddersfield.
Brighton and Hove Albion v Sheffield Wednesday
Sheffield Wednesday are the only other club in the division without a win and they are on the road to the Amex Stadium to take on Brighton and Hove Albion.
The Owls have collected four points from their first eight games - their worst start to a campaign since 1999 - while Brighton's 2-0 defeat at Ipswich on Saturday ended their six-match unbeaten run.
In the last four meetings between the two clubs, the home side has been victorious - the Seagulls won 3-0 at the Amex in September last year and Wednesday triumphed 3-1 in the February clash at Hillsborough.
Charlton Athletic v Nottingham Forest
Charlton Athletic have suffered three successive defeats and welcome Nottingham Forest.
Chris Powell's Addicks haven't succumbed to four losses on the spin since 2011 but that will be the case if they falter against Forest, who are unbeaten in four but without an away win since the beginning of August.
Charlton's only three-pointer so far came at The Valley against Leicester, while Forest's solitary loss to date was at Wigan Athletic.
Derby County v Ipswich Town
Derby County's life under the stewardship of Steve McClaren begins at home to Ipswich Town on Tuesday.
McClaren was installed as the Rams' boss on Monday following Saturday night's dismissal of Nigel Clough, whose sacking came after a 1-0 loss to rivals Nottingham Forest, which left the team sitting 14th.
Ipswich haven't looked back since they appointed Mick McCarthy last November and Saturday's 2-0 win against Brighton was their third win in four.
Steve McClaren poses for the cameras after being appointed as Derby's new boss
Doncaster Rovers v Burnley
Burnley are up to second and take on Doncaster Rovers at the Keepmoat Stadium.
The Clarets have chalked up three successive wins, culminating in Saturday's 3-0 win over Charlton, and the run they are on is their best start for 12 years.
Doncaster ended a five-match winless streak by beating Yorkshire rivals Sheffield Wednesday 1-0 at the weekend with Manchester United loanee Frederico Macheda netting his third goal in two games.
Leeds United v Bournemouth
Leeds have hit a sticky patch of form and host Bournemouth.
Brian McDermott's men have lost to Reading, Burnley and Millwall in their last three outings but they hold a 100 per cent home League record against the Cherries, winning all four of their meetings at Elland Road.
Bournemouth, who have never got the better of Leeds, have experienced an inconsistent start, winning four and losing four of their opening nine.
Middlesbrough v Huddersfield Town
The Sky Bet Championship's draw specialists Middlesbrough are at home to Huddersfield.
Five of Boro's last seven have finished level with the other two, including their most recent match, ending in defeat. Their only victory to date came against Charlton in the second week of the season.
Huddersfield have started very well and sit eighth on 13 points. They have shared the points in three of their last four matches.
Yeovil Town v Leicester City
Yeovil Town continue to struggle and entertain Leicester City.
The Glovers' five points from their first nine outings is their worst start to a Football League season and they are without a three-point haul since the opening day when they overcame Millwall at The Den.
The Foxes have registered 10 points from the last 12 on offer and could go top if they win and other results go their way.
The two meetings between these two clubs - in the 2008/09 League 1 season - went Leicester's way, with Yeovil failing to score on both occasions.