Brentford v Carlisle United
Brentford remain unbeaten in Sky Bet League 1 and they welcome struggling Carlisle United on Saturday.
The Bees have two wins and two draws to their name so far to sit fourth and that's a far cry from the situation at Carlisle, who have just a single point, which only came last time out in a 1-1 draw with Colchester United.
The Cumbrians have shipped 14 goals in their four games, scoring just two, and manager Greg Abbott will need to address that if his side are to start climbing the table.
Colchester United v Leyton Orient
That draw for Colchester against Carlisle extended their unbeaten start to the season but they have their toughest test yet on Saturday against table-topping Leyton Orient.
The Os have a 100 per cent record with wins against Carlisle, Shrewsbury, Stevenage and, most recently, Crewe Alexandra, and they have conceded just once in those matches.
Colchester were victorious in their opening two but have been held to draws in their last two, leaving them fifth on eight points.
Gillingham v Bristol City
Gillingham and Bristol City both have two points on the board and they clash at the Priestfield Stadium.
The Gills were promoted from League 2 as champions last term and their two points to date have come from their most recent two outings, when they shared the spoils with Brentford and then Swindon Town.
The Robins, who were relegated from the Championship, have drawn 2-2 with both Bradford City and Milton Keynes Dons, with two defeats sandwiched in between.
Notts County v Rotherham United
Notts County remain in search of their first three-point haul of the campaign and they host Rotherham United.
The Magpies have just a point to show from their first four League 1 matches but will take confidence from their midweek Capital One Cup exploits when they took Liverpool to extra-time, eventually losing 4-2 after a 2-2 draw.
Rotherham remain unbeaten following their promotion from League 2 last season. Steve Evans' Millers have notched three draws and a win to date.
Oldham Athletic v Tranmere Rovers
Tranmere Rovers are another team still on the hunt for a first victory of the campaign and they are on the road to Oldham.
Ronnie Moore's team have conceded 13 goals in four matches - against Walsall, Crawley Town, Crewe and Peterborough United - and those fixtures have yielded just a solitary point.
The Latics will be satisfied with their start - Lee Johnson's men have two wins and two defeats to lie eighth.
Peterborough United v Crawley Town
Peterborough United have made a flying start to the campaign to sit alongside Leyton Orient at the summit and this Saturday they entertain Crawley.
Posh have found the net 12 times in four matches, all of which have ended in wins, to get their promotion push off to the perfect start.
Like Peterborough, Crawley also began the season well, with a victory and a win in their first two, but they have since lost to Rotherham United and Wolverhampton Wanderers.
Port Vale v Wolverhampton Wanderers
After an action-packed finale in their previous game, Wolves are back in action on Saturday against Port Vale at Vale Park.
Kenny Jackett's side were pegged back late on against Crawley in their last league outing only for Kevin McDonald to win a penalty seconds later which was lashed home by Leigh Griffiths to maintain their positive start.
Port Vale were on the end of a 2-1 defeat to Oldham in their most recent match but that followed a 2-1 win against Bradford City, which was their first triumph of the campaign.
Sheffield United v Milton Keynes Dons
Following a Yorkshire derby defeat to Bradford City, Sheffield United host Milton Keynes Dons.
The Blades fell to their second loss of the campaign against the Bantams courtesy of a Nahki Wells brace. That result means David Weir's side have not won since beating Notts County on the opening day, and their only other point came from a 1-1 draw with Colchester.
MK Dons are yet to taste defeat but have been held to draws in three of their four league games so far. The Dons twice came from behind to share the points with Bristol City last weekend.
Shrewsbury Town v Coventry City
High-scoring Coventry City make the trip to Shropshire where they will be entertained by Shrewsbury Town.
The Sky Blues are League 1's highest scorers with 15 goals from their first four outings and come into the match in good form after successes against Bristol City and Carlisle, before an eight-goal draw against Preston North End last Sunday.
Graham Turner's Shrews took the lead twice in their most recent match with goals from Jon Taylor and Tom Bradshaw but were unable to hold on, eventually drawing 2-2 against Rotherham.
Stevenage v Bradford City
Nahki Wells will be aiming to continue his record-breaking scoring streak when Bradford City and Stevenage meet at Lamex Stadium.
Wells netted a brace against Yorkshire rivals Sheffield United last weekend to lift Bradford's points tally to seven from four games and, by doing so, he broke a City record of scoring in eight consecutive matches.
James Dunne hit an injury-time winner against Notts County to ensure Graham Westley's Boro got off the mark last Saturday. That 1-0 win was followed by a fighting performance in their midweek Capital One Cup loss against Premier League Everton - Luke Freeman gave Stevenage the lead but they eventually went down 2-1 in extra-time.
Swindon Town v Crewe Alexandra
Swindon Town will be buoyant from their Capital One Cup win against Championship opposition and they welcome Crewe Alexandra on Saturday.
The Robins have struggled in the league so far, winning just once, but will be confident following a 2-0 win over Queens Park Rangers on Tuesday night, which secured their place in the third round.
Crewe also have just a solitary win under their belts - a 2-1 success against Tranmere Rovers two weeks ago.
Walsall v Preston North End
The Football League's draw specialists Preston North End are entertained by Walsall.
Simon Grayson's men have opened the season with four draws from four, the latest of which ended 4-4 against Coventry City.
Walsall lost for the first time last weekend, going down 1-0 to Brentford, but have the upper hand in recent encounters with North End, winning five of the last six meetings, including both games last term.
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