Victory for the Blades will open up an eight-point lead over their opponents, and Bolton Wanderers will be keeping an eye on proceedings – they could leapfrog the Iron with three points at Bradford City.
Fleetwood Town travel to Milton Keynes Dons looking to extend their 16-game unbeaten run, while there are some crucial matches at the other end of the table.
Chesterfield and Bury are both in the relegation zone and lock horns, with Lee Clark taking charge of the Shakers for the first time, while Swindon Town host Oldham Athletic in another battle between two struggling sides.
Sky Bet League One: Matchday 33 fixtures (3pm kick-off)
Saturday 18th February 2017
Bradford City v Bolton Wanderers
Chesterfield v Bury
Coventry City v Gillingham
Milton Keynes Dons v Fleetwood Town
Port Vale v Bristol Rovers
Rochdale v Charlton Athletic
Sheffield United v Scunthorpe United
Shrewsbury Town v AFC Wimbledon
Southend United v Northampton Town
Swindon Town v Oldham Athletic
Walsall v Peterborough United
Referees: Click here to see who's on duty in the Sky Bet League OneFive facts
1. Bradford's last home win against Bolton came in 1993, although they have only hosted the Trotters three times since – this will be the first Valley Parade meeting since a 2-2 draw in 1998.
2. Chesterfield have won four of their last five home fixtures against Bury without conceding a goal. The only time they did concede during that run, they lost – a 3-2 reverse in 2011.
3. Coventry and Gillingham meet in a league fixture for the 50th time, with Coventry holding the bragging rights courtesy of 24 triumphs to the Gills' 15. The spoils have been shared 10 times.
4. Fleetwood need to do something they've never done before if they are to extend their impressive unbeaten run, and that's avoid defeat against MK Dons – they've lost all three previous meetings.
5. Loss, draw, loss, draw, loss... that's how Swindon's home form reads over their last five matches against Oldham, but they did get the upper hand with a 2-0 away win earlier this season.
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