The Sky Bet League Two Chairboys beat non-league Stourbridge in round three to set-up the tie at White Hart Lane, and Ainsworth was thrilled with the news.
The manager was travelling up to Blackpool for his side's Checkatrade Trophy game when the draw was revealed, meaning he wasn't in the club's video, which has gone viral.
"For me, it’s the best draw of the round and it’s great for everyone involved with the club to look forward to," Ainsworth, who has guided Wycombe to fifth in League Two after 24 games this term, said.
“I’ve seen the video of the boys reacting to the draw at the hotel and it shows what a special competition this is. There’s a fabulous spirit around this club and I’m sure that will only grow as the game gets nearer.
“My boys will give their all to make more memories for Wycombe Wanderers fans who I know will be there in great numbers getting right behind us.”
Draw: Click here to see who other EFL teams will play in the FA Cup fourth round